Chemicals and Cancer

Reactive Chemicals and Electrophilic Stress in Cancer

Exogenous reactive chemicals can impair cellular homeostasis and are often associated with the progression of cancer. Significant progress has been achieved by studying the interactions of chemicals that possess various electron-withdrawing groups and the elucidation of the protective responses of cells to chemical interventions. However, the formation of electrophilic species inside the cell r...

Chemicals and Infertility at a Glance

We can eliminate occupational cancer from chemicals.

EDITORIAL We can eliminate occupational cancer from chemicals We no longer send children to work crawling up chimneys sweeping out soot, nor do we allow men to rip out asbestos insulation in shipyards without any controls. However , there are still chimney sweeps and asbestos workers and there are still cancer risks associated with their work. Well over a million men and women in Great Britain ...

Endocrine disrupting chemicals and cancer risk (testis and breast)

There has been much concern whether Endocrine Disrupting Chemicals (EDCs) play a role in the recent increase in the incidence of certain hormone sensitive cancer forms. There is at present, however, no proven causal link between exposure to EDCs and human cancer in any of the organs supposed to be at highest risk, i.e., the testis, breast, prostate, and endometrium. This may be due to a real ab...

Chemicals, industrial processes and industries associated with cancer in humans.

The programme on the Evaluation of the Carcinogenic Risk of Chemicals to Humans has existed since 1971 and involves the preparation and publication of monographs that evaluate individual chemicals and, more recently, carcinogenic risks resulting from exposures to complex mixtures, since it is in this way that human populations are often exposed. Exposures occurring in the wood and leather indus...